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Study identifier: NCT07461909 Synced from ClinicalTrials.gov · July 28, 2026
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Comparison of Two Vaginal Progesterone Forms in Frozen Embryo Transfer

Condition: Frozen Embryo Transfer (FET) · Infertility · Artificial Cycle  ·  Sponsor: Instituto Valenciano de Infertilidade de Lisboa

PhaseN/A
Planned participants400
Who can joinFemale, 18 Years to 48 Years
Healthy volunteersNo

About this study

The goal of this observational study is to compare two commonly used vaginal progesterone formulations - soft capsules versus pessaries - in women undergoing frozen embryo transfer (FET). The main question it aims to answer is: \- Do soft vaginal progesterone capsules provide similar or better patient satisfaction, convenience, and tolerability compared with vaginal progesterone pessaries during preparation for frozen embryo transfer? Participants undergoing FET who are prescribed vaginal progesterone as part of their endometrial preparation and luteal phase support will use one of the two formulations and complete patient-reported assessments regarding satisfaction, convenience, and tolerability. The study will also measure serum progesterone levels on the day of embryo transfer and evaluate pregnancy outcomes, including clinical pregnancy and live birth rates.

This description comes directly from the study's public registry record.

Talk to the study team

Samuel Ribeiro  ·  +351 218503210  ·  Samuel.Ribeiro@ivirma.com

Belisa Silva  ·  +351 218503210  ·  Belisa.Silva@ivirma.com

Always discuss trial participation with your own doctor first.

Locations (1)

Instituto Valenciano de Infertilidade (IVI Lisboa)Lisbon, PortugalRecruiting

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Source record: clinicaltrials.gov/study/NCT07461909