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Study identifier: NCT07461220 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Safety and Tolerability of IRL757 in Participants With Parkinson's Disease and Apathy

Condition: PARKINSON DISEASE (Disorder) · Apathy · Safety  ·  Sponsor: Integrative Research Laboratories AB

PhasePhase 1/Phase 2
Planned participants75
Who can joinAll sexes, 50 Years to 90 Years
Healthy volunteersNo

About this study

This clinical trial's goal is to evaluate if the IRL757 is safe and has a good tolerability in participants with Parkinson's disease and experiencing apathy (a lack of interest or motivation). In addition, the trial is aiming to learn if IRL757 has effects on the symptoms of Parkinson's disease. Researchers will compare the effects of IRL757 to a placebo (a look-alike substance that contains no drug). Participants who fit the study criteria will be treated with the study drug (either the active drug IRL757 or placebo) for 12 weeks and will visit the clinic at 5 defined timepoints for check-ups and tests. A follow-up call after the end of treatment will be done 4 weeks after the last study drug intake.

This description comes directly from the study's public registry record.

Talk to the study team

Joakim Tedroff  ·  +46 31 757 38 00  ·  info@irlab.se

Always discuss trial participation with your own doctor first.

Locations (13)

Medical Center "Galileo" OODPleven, BulgariaRecruiting
First University Multiprofile Hospital for Active Treatment MHAT - Neurology ClinicSofia, BulgariaRecruiting
University Multiprofile Hospital for Active Treatment "Alexandrovska" EAD, Clinic of Neurological DiseasesSofia, BulgariaNot Yet Recruiting
Neurologie BerlinBerlin, GermanyRecruiting
Universitaetsklinikum Carl Gustav CarusDresden, GermanyNot Yet Recruiting
Centrum Medyczne NEUROMEDBydgoszcz, PolandRecruiting
Neuro-Care sp. z o.o. sp. KomandytowaKatowice, PolandRecruiting
NeuroKlinika Prof. Andrzej BoguckiLodz, PolandRecruiting
EuroMedis Sp. z o.o.Szczecin, PolandRecruiting
Centrum Medyczne NeuroProtectWarsaw, PolandNot Yet Recruiting
Hospital de la Santa Creu i Sant Pau, Unidad de trastornos del movimientoBarcelona, SpainRecruiting
Hospital General Universitario de ElcheElche, SpainNot Yet Recruiting

+ 1 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07461220