Condition: Stuttering, Developmental · Dyslexia · Healthy Participants · Sponsor: Boston University Charles River Campus
This study aims to understand how people use different types of feedback to control their speech. When an individual speaks, the brain relies on several systems at the same time, such as sensory systems that monitor an individuals own voice and the movements of their speech muscles, and a motor system that builds and reads out learned motor patterns. The investigators are studying how these systems work together and how they differ across individuals. Investigators will test 90 adults between 18 and 50 years old, including people who stutter, people with dyslexia, and people with typical speech and reading development. Participants will complete several short speech tasks in which the sounds they hear or the movements of their jaw or larynx are briefly changed. These responses will be used to measure each person's speech motor skills and to estimate the settings of a computer model called "SimpleDIVA," which simulates how the brain controls speech. Participants will also complete an MRI scan so investigators can measure the structure and connectivity of different brain regions. These measures will help investigators understand how individual differences in the brain relate to the speech motor control skills we observe. Participants will also complete sessions with noninvasive brain stimulation (transcranial current stimulation, or tCS) to examine how stimulation of specific areas of the brain affects responses during the speech tasks. The knowledge gained from this study w…
This description comes directly from the study's public registry record.
Frank H Guenther, Ph.D. · 617-353-5765 · guenther@bu.edu
Barbara G Holland, M.A. · 617-353-6181 · hollandb@bu.edu
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| Boston University Charles River Campus | Boston, Massachusetts, United States | Recruiting |
| Boston University | Boston, Massachusetts, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07459803