← Eichor
Study identifier: NCT07458347 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Phase 1 Dose-escalation Trial of KST-6051 in Participants With Advanced Solid Tumors With Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Mutation

Condition: KRAS-mutant Non-small Cell Lung Cancer (NSCLC) · KRAS-mutant Pancreatic Ductal Adenocarcinoma (PDAC) · KRAS-mutant Colorectal Cancer (CRC)  ·  Sponsor: Kestrel Therapeutics, Inc.

PhasePhase 1
Planned participants145
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The main purpose of the trial is to assess whether the trial drug, KST-6051, is safe and tolerable when administered orally to adults with advanced or metastatic solid tumors with certain KRAS mutations.

This description comes directly from the study's public registry record.

Talk to the study team

Kestrel Therapeutics, Inc.  ·  617-612-6810  ·  clinicaltrials@kestreltherapeutics.com

Always discuss trial participation with your own doctor first.

Locations (9)

Cedars-Sinai Medical CenterLos Angeles, California, United StatesRecruiting
Florida Cancer SpecialistsSarasota, Florida, United StatesRecruiting
Moffitt Cancer CenterTampa, Florida, United StatesRecruiting
Mass General Brigham Cancer Institute at Massachusetts General HospitalBoston, Massachusetts, United StatesRecruiting
Sidney Kimmel Cancer CenterPhiladelphia, Pennsylvania, United StatesRecruiting
The University of Texas MD Anderson Cancer CenterHouston, Texas, United StatesRecruiting
NEXT OncologySan Antonio, Texas, United StatesRecruiting
Huntsman Cancer Institute, University of UtahSalt Lake City, Utah, United StatesRecruiting
NEXT VirginiaFairfax, Virginia, United StatesRecruiting

Follow this study

Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.

We email about this public record only. Unsubscribe anytime with one click. Never medical advice.

Is this your study? This page was generated automatically from the public registry record. Sponsors can claim it — free — to add branding and verified contact routing. Claim this page →

This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.

Source record: clinicaltrials.gov/study/NCT07458347