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Study identifier: NCT07456163 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Influence of Zirconia Abutments on Peri-Implant Tissues in Single-Tooth Restorations

Condition: Peri-Implant Health · Implant Complication · Prosthesis and Implants  ·  Sponsor: University of Campinas, Brazil

PhaseNA
Planned participants71
Who can joinAll sexes, 18 Years to 70 Years
Healthy volunteersYes

About this study

Objectives: To compare the influence of pre-fabricated titanium abutments and customized milled zirconia abutments on implant biocompatibility and the peri-implant region, as well as on radiographic bone loss and oral health-related quality of life. Detailed Methodology: This study is a randomized controlled clinical trial designed to evaluate the biological and clinical behavior of standardized titanium abutments compared with customized anatomical zirconia abutments in single implant-supported posterior restorations. The present investigation represents the prosthetic phase of a previously conducted randomized clinical trial that evaluated dimensional changes following different alveolar preservation protocols in posterior regions (CAAE: 59208422.8.0000.5418). In the previous phase, participants underwent tooth extraction and alveolar preservation procedures, followed by implant placement with Morse Taper (CM) implants (Biomorse XP, Bionnovation Biomedical) after a six-month healing period. After implant osseointegration, participants eligible for prosthetic rehabilitation will be randomly allocated to one of two parallel groups using a computer-generated randomization sequence (Sealedenvelope.com). The allocation ratio will be 1:1. Sample size calculation was performed using GPower software to ensure adequate statistical power. The intervention consists of prosthetic rehabilitation with either standardized titanium abutments (TiB group) or customized anatomical zirconia…

This description comes directly from the study's public registry record.

Talk to the study team

Leticia Sandoli Arroteia, Ms and PhD Student  ·  +5514981600821  ·  leticia.sandoli@hotmail.com

Always discuss trial participation with your own doctor first.

Locations (1)

Piracicaba Dental SchoolPiracicaba, São Paulo, BrazilRecruiting

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Source record: clinicaltrials.gov/study/NCT07456163