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Study identifier: NCT07454915 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

PVX4 for the Treatment of Human Papilloma Virus (HPV)16+ Cervical Dysplasia

Condition: Cervical Intraepithelial Neoplasia Grade 2/3 · Human Papilloma Virus Infection Type 16  ·  Sponsor: PapiVax Biotech, Inc.

PhasePhase 2
Planned participants138
Who can joinFemale, 18 Years to 60 Years
Healthy volunteersNo

About this study

The purpose of this Phase 2 study is to compare the effects of administering the PVX4 combination device biologic product (pBI-4 DNA vaccine via electroporation-mediated intramuscular delivery with the TriGrid™ Delivery System) in patients with biopsy-confirmed, human papilloma virus (HPV) 16-associated high grade cervical intraepithelial neoplasia (CIN2/3) as compared to the administration of placebo.

This description comes directly from the study's public registry record.

Talk to the study team

Contact details are listed per location below or on the registry record.

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Locations (10)

Montefiore Medical CenterThe Bronx, New York, United StatesNot Yet Recruiting
Kaohsiung Chang Gung Memorial HospitalKaohsiung, Taiwan, TaiwanNot Yet Recruiting
China Medical University HospitalTaichung, Taiwan, TaiwanNot Yet Recruiting
Taichung Veterans General HospitalTaichung, Taiwan, TaiwanNot Yet Recruiting
National Cheng Kung University HospitalTainan, Taiwan, TaiwanNot Yet Recruiting
National Taiwan University HospitalTaipei, Taiwan, TaiwanNot Yet Recruiting
MacKay Memorial HospitalTaipei, Taiwan, TaiwanNot Yet Recruiting
Taipei Medical University HospitalTaipei, Taiwan, TaiwanNot Yet Recruiting
Taipei Veterans General HospitalTaipei, Taiwan, TaiwanNot Yet Recruiting
Linkou Chang Gung Memorial HospitalTaoyuan, Taiwan, TaiwanRecruiting

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Source record: clinicaltrials.gov/study/NCT07454915