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Study identifier: NCT07454824 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

e-ALIGN: A Patient Portal-based Intervention to Align Medications With What Matters Most

Condition: Dementia · Potentially Inappropriate Medication Use · Mild Cognitive Impairment (MCI)  ·  Sponsor: Johns Hopkins University

PhaseNA
Planned participants100
Who can joinAll sexes, 65 Years to no upper limit
Healthy volunteersYes

About this study

The overarching goal of this study is to pilot an intervention in which older adults with mild cognitive impairment and dementia and the older adult's care partners are identified in primary care and provided with educational materials through the patient portal to engage the participant in deprescribing. The multicomponent intervention, e-Align, includes delivery of educational information through the patient portal, and a pharmacist-led intervention to align medications with patient and care partner goals and reduce use of central nervous system (CNS) potentially inappropriate medicines (PIM). This work will establish the preliminary data, methods, and partnerships to undertake a multisite embedded pragmatic clinical trial. The resulting triadic-based behavioral intervention will promote patient and care partner engagement, and foster care that aligns with patients' values, and promote improved health and well-being outcomes for people with cognitive impairment and the patient's care partners through deprescribing.

This description comes directly from the study's public registry record.

Talk to the study team

Ariel Green, MD, MPH, PhD  ·  410-550-6733  ·  ariel@jhmi.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Johns Hopkins Community PhysiciansBaltimore, Maryland, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07454824