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Study identifier: NCT07454642 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

AVA6103 in Subjects With Locally Advanced or Metastatic Selected Solid Tumors

Condition: Vulvar Adenocarcinoma · PDAC - Pancreatic Ductal Adenocarcinoma · Gastric Adenocarcinoma  ·  Sponsor: Avacta Life Sciences Ltd

PhasePhase 1
Planned participants174
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a first-in-human (FIH), Phase 1 open-label, multicenter dose escalation study investigating AVA6103 monotherapy administered intravenously in patients with locally advanced (unresectable) or metastatic solid tumors that are likely to be FAP positive. The study consists of an initial Phase 1a dose escalation portion and a subsequent Phase 1b dose expansion portion upon completion of the dose escalation portion.

This description comes directly from the study's public registry record.

Talk to the study team

Avacta Clinical Team  ·  +44 (0)20 3911 0353  ·  clinicaltrials@avacta.com

Always discuss trial participation with your own doctor first.

Locations (3)

START MidwestGrand Rapids, Michigan, United StatesRecruiting
NEXT OncologyIrving, Texas, United StatesRecruiting
NEXT Oncology VirginiaFairfax, Virginia, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07454642