Condition: Pre-Frailty · Aging · Sponsor: National University of Singapore
Frailty is associated with biological changes in the gut microbiome and immune system, along with marked declines in physical and cognitive function, leading to an overall reduction in quality of life. Prefrailty represents an early stage where interventions may prevent or reverse these declines. This study aims to evaluate whether a 12-week combined Synbiotic enriched oral nutritional supplement and supervised exercise program can improve muscle strength and mass, gut microbiome composition, immune function, and cognitive performance in prefrail adults aged 50-80 years.
This description comes directly from the study's public registry record.
Mazzarine Dotou, PhD · +65 87264704 · mazzarine@nus.edu.sg
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| MD11 Clinical Research Centre, #03-01, 10 Medical Drive | Singapore, Singapore | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07454616