← Eichor
Study identifier: NCT07454291 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Study to Evaluate Pharmacokinetics and Drug-drug Interactions of ENV-101 (Taladegib) in Healthy Participants

Condition: Idiopathic Pulmonary Fibrosis  ·  Sponsor: Endeavor Biomedicines, Inc.

PhasePhase 1
Planned participants57
Who can joinAll sexes, 26 Years to 65 Years
Healthy volunteersYes

About this study

The purposes of this study are to: 1. evaluate potential interactions between taladegib (ENV-101) and current standard-of-care (SOC) therapies for idiopathic pulmonary fibrosis (IPF), including nintedanib and pirfenidone, and 2. more fully characterize the pharmacokinetics (PK) of taladegib (i.e., how the body absorbs, distributes, metabolizes and excretes taladegib). This study will enroll 4 cohorts (groups) of participants. Each cohort will experience a different duration of treatment and sequestering (being housed) at the clinical site, followed by a 14-day follow-up period for safety evaluation. The longest duration of treatment for any cohort is 30 days.

This description comes directly from the study's public registry record.

Talk to the study team

Endeavor Clinical Trials  ·  1-858-727-3199  ·  ebmclinical@endeavorbiomedicines.com

Always discuss trial participation with your own doctor first.

Locations (2)

Research SiteBrisbane, Queensland, AustraliaRecruiting
Research SiteMelbourne, Victoria, AustraliaRecruiting

Follow this study

Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.

We email about this public record only. Unsubscribe anytime with one click. Never medical advice.

Is this your study? This page was generated automatically from the public registry record. Sponsors can claim it — free — to add branding and verified contact routing. Claim this page →

This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.

Source record: clinicaltrials.gov/study/NCT07454291