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Study identifier: NCT07453862 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Novel Calcium Channel Modulators in RLS and Variants: Efficacy & Safety

Condition: Restless Leg Syndrome (RLS) · Variant Restless Legs Syndrome  ·  Sponsor: Beijing Friendship Hospital

PhasePhase 1
Planned participants20
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

The goal of this \[study type: clinical trial\] is to \[primary purpose: evaluate the efficacy and safety of a novel calcium channel modulator in treating Restless Legs Syndrome (RLS) and its variant subtypes\] in \[describe participant population/primary condition: adult patients aged 18-75 years with confirmed RLS or its variant subtypes, who meet the study's eligibility criteria\]. The main question\[s\] it aims to answer \[is/are\]: * Does the novel calcium channel modulator improve RLS-related symptoms (assessed by the International Restless Legs Syndrome Study Group Rating Scale, IRLS) after the treatment period? * What is the safety profile (incidence of adverse events) of this calcium channel modulator in RLS patients? Participants will \[describe the main tasks participants will be asked to do, interventions they'll be given\]: * Receive oral administration of the novel calcium channel modulator (40mg twice daily) for 12 consecutive weeks * Complete scheduled follow-up visits for symptom assessments, safety monitoring, and questionnaire completion

This description comes directly from the study's public registry record.

Talk to the study team

Wenlu Zhao  ·  13017688128  ·  912977992@qq.com

Always discuss trial participation with your own doctor first.

Locations (1)

Capital Medical University Affiliated Beijing Friendship HospitalBeijing, Beijing Municipality, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07453862