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Study identifier: NCT07453823 Synced from ClinicalTrials.gov · July 29, 2026
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The Effect of a Synbiotic on Intestinal Barrier Function and Microbiota Modulation in Middle-aged to Elderly Individuals With Excessive Body Weight

Condition: Gastrointestinal Microbiome (Focus) · Gastrointestinal Symptoms  ·  Sponsor: Chr Hansen - part of Novonesis

PhaseNA
Planned participants90
Who can joinAll sexes, 50 Years to 70 Years
Healthy volunteersYes

About this study

The study is a single-center, randomized, double-blind, placebo-controlled study in middle-aged to elderly adults with excessive body weight. The study includes an 8-week intervention period followed by a 2-week follow-up period. The study will evaluate the effect of a synbiotic consisting of two probiotic strains and a prebiotic. The aim is to investigate the effect of the synbiotic on modulating the gut microbiota and improving markers of gastrointestinal permeability and integrity and gastrointestinal discomfort.

This description comes directly from the study's public registry record.

Talk to the study team

Sara Engel, PhD  ·  +45 45 74 74 74  ·  saen@novonesis.com

Emma Harrington  ·  eharrington@atlantiatrials.com

Always discuss trial participation with your own doctor first.

Locations (1)

Atlantia Clinical Trials LtdCork, Blackpool, IrelandRecruiting

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Source record: clinicaltrials.gov/study/NCT07453823