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Study identifier: NCT07453602 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Ph 1a/1b Single Ascending Dose and Multiple Ascending Dose Study of ARQ-234

Condition: Atopic Dermatitis (AD) · Eczema  ·  Sponsor: Arcutis Biotherapeutics, Inc.

PhasePhase 1
Planned participants125
Who can joinAll sexes, 18 Years to 65 Years
Healthy volunteersYes

About this study

This is a first-in-human, Phase 1, double-blind, randomized, placebo-controlled, dose-escalation study evaluating ARQ-234. The study is designed to assess the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of ARQ-234 in two populations: healthy volunteers and participants with moderate to severe atopic dermatitis (AD). Healthy volunteers will participate in Single Ascending Dose (SAD) Cohorts 1-5. Participants with moderate to severe AD will be enrolled in SAD Cohorts 6-7, Multiple Ascending Dose (MAD) Cohorts, and a Proof-of-Concept (POC) expansion cohort.

This description comes directly from the study's public registry record.

Talk to the study team

Arcutis Medical Information  ·  1-844-692-6729  ·  medinfo@arcutis.com

Always discuss trial participation with your own doctor first.

Locations (1)

Clinical Site 101Fair Lawn, New Jersey, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07453602