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Study identifier: NCT07450547 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Phase 2 Study to Assess the Safety and Efficacy of ANG003

Condition: Exocrine Pancreatic Insufficiency (EPI) · Cystic Fibrosis (CF)  ·  Sponsor: Anagram Therapeutics, Inc.

PhasePhase 2
Planned participants113
Who can joinAll sexes, 12 Years to no upper limit
Healthy volunteersNo

About this study

In this study, ANG003, a pancreatic enzyme replacement therapy (PERT; commonly called "enzymes"), is being investigated as a potential treatment for exocrine pancreatic insufficiency (EPI). People with EPI due to Cystic Fibrosis (CF) may be eligible to participate in this study. The primary objective of this study is to evaluate the safety of ANG003 and see if it works as well compared to Creon, an approved PERT.

This description comes directly from the study's public registry record.

Talk to the study team

Evan Bailey, MD  ·  617-466-3111  ·  medical@anagramtx.com

Always discuss trial participation with your own doctor first.

Locations (26)

Long Beach Memorial Medical CenterLong Beach, California, United StatesRecruiting
Center for Cystic Fibrosis at Keck Medical Center of USCLos Angeles, California, United StatesNot Yet Recruiting
National Jewish HealthDenver, Colorado, United StatesNot Yet Recruiting
University of FloridaGainesville, Florida, United StatesNot Yet Recruiting
Central Florida Pulmonary GroupOrlando, Florida, United StatesNot Yet Recruiting
The Cystic Fibrosis InstituteGlenview, Illinois, United StatesRecruiting
University of IowaIowa City, Iowa, United StatesNot Yet Recruiting
University of Kansas Medical CenterKansas City, Kansas, United StatesNot Yet Recruiting
University of KentuckyLexington, Kentucky, United StatesNot Yet Recruiting
MaineHealth Pediatric Specialty CarePortland, Maine, United StatesNot Yet Recruiting
Massachusetts General HospitalBoston, Massachusetts, United StatesNot Yet Recruiting
Boston Children's HospitaBoston, Massachusetts, United StatesNot Yet Recruiting

+ 14 more locations — full list on the registry record.

Follow this study

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Source record: clinicaltrials.gov/study/NCT07450547