Condition: Epstein-Barr Virus-Associated Lymphoproliferative Disorders · EBV-Positive Lymphoma · Sponsor: Daihong Liu
This is an investigator-initiated, open-label, single-arm, dose-escalation exploratory study to evaluate the safety, tolerability, and preliminary efficacy of EBV-AST cell injection in adults with EBV-associated lymphoproliferative disorders, including post-transplant lymphoproliferative disease (PTLD) and EBV-positive lymphomas. Participants will receive EBV-AST cell infusions intravenously every 2 weeks for up to 3 infusions at escalating dose levels. The primary objective is to assess safety and determine a potential optimal biologically active dose. Secondary objectives include preliminary tumor response and EBV-related virologic outcomes, as well as cellular PK/PD.
This description comes directly from the study's public registry record.
Daihong Liu · +8613681171597 · daihongrm@163.com
Liping Dou · +8613681207138 · lipingruirui@163.com
Always discuss trial participation with your own doctor first.
| Chinese PLA General Hospital | Beijing, Beijing Municipality, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07450391