Condition: Obesity · Sponsor: General Committee of Teaching Hospitals and Institutes, Egypt
Obesity is a global health problem that has reached epidemic proportions, affecting more than one billion people worldwide and significantly increasing the risk of multiple comorbidities, including type 2 diabetes, cardiovascular diseases, and cancer (World Health Organization, 2024). Increasing evidence suggests that chronic low-grade inflammation associated with obesity plays a critical role in the development of obesity-related malignancies, including gastric cancer. Adipose tissue dysfunction in obesity leads to the recruitment and activation of various immune cells, such as macrophages and mast cells, which contribute to a pro-inflammatory microenvironment through the release of cytokines, growth factors, and angiogenic mediators.
This description comes directly from the study's public registry record.
Mohamed H Ashour, PhD · 00201002600970 · dr.mhany@gmail.com
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| The surgical department of Medical Research Institute Hospital, Alexandria University | Alexandria, Alexandria Governorate, Egypt | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07448896