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Study identifier: NCT07445971 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study Evaluating MDX2301 in Healthy Adults and Adults at Higher Risk for Severe COVID-19.

Condition: COVID -19 · COVID-19 (Prevention)  ·  Sponsor: ModeX Therapeutics, An OPKO Health Company

PhasePhase 1
Planned participants80
Who can joinAll sexes, 18 Years to 64 Years
Healthy volunteersYes

About this study

This first-in-human study is designed to evaluate the safety, tolerability, pharmacokinetics, anti-drug antibodies, and neutralizing activity of MDX2301 administered by intravenous (IV), intramuscular (IM), or subcutaneous (SC) routes in healthy adults and adults at higher risk for severe COVID-19. Participants will receive single IV, IM, and SC doses of MDX2301 or placebo and a repeat IM or SC dose approximately 3 months apart of MDX2301 or placebo.

This description comes directly from the study's public registry record.

Talk to the study team

ModeX Therapeutics, An OPKO Health Company  ·  857-233-9936  ·  info@modextx.com

Always discuss trial participation with your own doctor first.

Locations (2)

TrialMed Clinical Research UnitLas Vegas, Nevada, United StatesRecruiting
TrialMed Clinical Research UnitAustin, Texas, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07445971