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Study identifier: NCT07445048 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Postoperative Radiotherapy Combined With Nimotuzumab Followed by Benmelstobart in High-Risk Patients With Head and Neck Squamous Cell Carcinoma

Condition: Head & Neck Squamous Cell Carcinoma · Head & Neck Cancer · Postoperative Adjuvant Treatment  ·  Sponsor: Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University

PhasePhase 3
Planned participants370
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

A Multicenter, Randomized, Controlled, Open-Label, Phase III Clinical Trial.To evaluate the efficacy and safety of postoperative radiotherapy combined with Nimotuzumab followed by Benmelstobart in high-risk patients with head and neck squamous cell carcinoma who are ineligible for cisplatin chemotherapy. The primary endpoint is disease-free survival (DFS). A total of 185 patients will be enrolled in both the study group and the control group, respectively, with a total planned enrollment of 370 patients. Enrollment is expected to be completed within 2 years, followed by a 3-year follow-up period after the last patient is enrolled.

This description comes directly from the study's public registry record.

Talk to the study team

Guopei Zhu  ·  23211699-5665  ·  antica@gmail.com

Shengjin Dou  ·  17521066068  ·  doushengjin@126.com

Always discuss trial participation with your own doctor first.

Locations (1)

Shanghai 9th people's hospitalShanghai, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07445048