Condition: Obstructive Sleep Apnea · Sleep Disorder (Disorder) · Atrial Fibrillation (AF) · Sponsor: Beijing Anzhen Hospital
Atrial fibrillation (AF) is one of the most common clinical arrhythmias. Catheter ablation is an effective therapeutic strategy; however, recurrence rates remain substantial, ranging from 20% to 45%. Previous studies have established a strong association between obstructive sleep apnea (OSA) and the risk of AF recurrence following ablation. While continuous positive airway pressure (CPAP) is the standard intervention for OSA, and some observational studies suggest it may reduce post-ablation recurrence in patients with comorbid OSA, small randomized controlled trials have failed to confirm a clear benefit, potentially due to poor adherence. This study aims to evaluate the clinical benefit of post-ablation CPAP therapy in AF patients with comorbid OSA. Participants will: * Be randomly assigned to either the CPAP group or the usual care group. * If in the CPAP group, use a CPAP device for 12 months. * Wear an ambulatory ECG recorder for a 7-day period at 3, 6, 9, and 12 months post-operation. * Complete follow-up checkups either at the clinic or over the phone at 1, 3, 6, and 12 months after their procedure.
This description comes directly from the study's public registry record.
Jiang Xie, Professor · +86 64456360 · frank782008@aliyun.com
Always discuss trial participation with your own doctor first.
| Beijing Chaoyang Hospital, Capital Medical University | Beijing, Beijing Municipality, China | Not Yet Recruiting |
| Beijing Anzhen Hospital | Beijing, Beijing Municipality, China | Recruiting |
| Beijing Jishuitan Hospital | Beijing, Beijing Municipality, China | Not Yet Recruiting |
| Beijing Hospital | Beijing, Beijing Municipality, China | Not Yet Recruiting |
| Peking University International Hospital | Beijing, Beijing Municipality, China | Not Yet Recruiting |
| Fujian Medical University Union Hospital | Fuzhou, Fujian, China | Not Yet Recruiting |
| First Affiliated Hospital of Fujian Medical University | Fuzhou, Fujian, China | Not Yet Recruiting |
| Zhangzhou Hospital of Fujian Province | Zhangzhou, Fujian, China | Not Yet Recruiting |
| People's Hospital of Guangxi Zhuang Autonomous Region | Nanning, Guangxi, China | Not Yet Recruiting |
| Langfang People's Hospital | Langfang, Hebei, China | Not Yet Recruiting |
| Shijiazhuang Great Wall Hospital of Integrated Traditional Chinese and Western Medicine | Shijiazhuang, Hebei, China | Not Yet Recruiting |
| The Ninth Hospital of Xingtai | Xingtai, Hebei, China | Not Yet Recruiting |
+ 15 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT07444372