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Study identifier: NCT07443943 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Dietary Supplement (Resistant Potato Starch) for Reducing Musculoskeletal Symptoms in Individuals Planning to Receive Aromatase Inhibitor Therapy, AIMSS-RPS Trial

Condition: Anatomic Stage 0 Breast Cancer AJCC v8 · Anatomic Stage I Breast Cancer AJCC v8 · Anatomic Stage II Breast Cancer AJCC v8  ·  Sponsor: University of Michigan Rogel Cancer Center

PhasePhase 2
Planned participants20
Who can joinAll sexes, N/A to no upper limit
Healthy volunteersYes

About this study

This phase II trial tests the safety and effectiveness of a dietary supplement called resistant potato starch for reducing musculoskeletal symptoms in patients with stage 0-III breast cancer or who are at high risk for breast cancer and are planning to receive treatment with an aromatase inhibitor. Aromatase inhibitors are a type of drug commonly used for the treatment or prevention of breast cancer. Many people who receive aromatase inhibitors experience musculoskeletal symptoms (symptoms relating to bones and muscles, such as joint pain or stiffness). Research has shown there may be an association between reduced levels of beneficial gut bacteria and the development of aromatase inhibitor-associated musculoskeletal symptoms. Resistant potato starch is a plant-based low-digestible carbohydrate that has the potential to promote the growth of beneficial gut bacteria. Taking resistant potato starch while receiving aromatase inhibitor therapy may reduce musculoskeletal symptoms in patients with stage 0-III breast cancer or individuals at high risk of developing breast cancer.

This description comes directly from the study's public registry record.

Talk to the study team

Cancer AnswerLine  ·  1-800-865-1125  ·  CancerAnswerLine@med.umich.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of Michigan Rogel Cancer CenterAnn Arbor, Michigan, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07443943