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Study identifier: NCT07443826 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

CALM-AF-AI: Counteracting Age-related Loss of Muscle With AAV-Follistatin Combined With Angiogenesis-Inducing VEGF Plasmid Gene Therapy

Condition: Age-related Muscle Decline  ·  Sponsor: Unlimited Biotechnology LLC

PhasePhase 1/Phase 2
Planned participants12
Who can joinAll sexes, 35 Years to 75 Years
Healthy volunteersYes

About this study

This Phase 1/2a, open-label, non-randomized study is designed to evaluate the safety and tolerability of intramuscular AAV9-Follistatin gene therapy administered either as monotherapy or in combination with a VEGF-encoding plasmid. Secondary objectives include the assessment of preliminary signals of biological and functional activity, including changes in skeletal muscle mass and performance.

This description comes directly from the study's public registry record.

Talk to the study team

Ivan Morgunov  ·  +31623454906  ·  ivan@unlimit.bio

Always discuss trial participation with your own doctor first.

Locations (1)

GARMCoxen Hole, Bay Islands, HondurasRecruiting

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Source record: clinicaltrials.gov/study/NCT07443826