Condition: Whole-Brain Radiotherapy · Sponsor: Cancer Institute and Hospital, Chinese Academy of Medical Sciences
This study is a multicenter, randomized, prospective Phase III study to evaluate the efficacy and safety of anlotinib plus whole-brain radiotherapy (WBRT) compared with WBRT alone in small cell lung cancer (SCLC) patients with brain metastases. Additionally, by investigating the association between changes in circulating tumor cell (CTC) levels in peripheral blood and treatment response to the combination of targeted therapy and radiotherapy, we aim to identify a patient subgroup most likely to benefit from this regimen, as well as potential biomarkers predictive of treatment efficacy.
This description comes directly from the study's public registry record.
Lei Deng, MD · +86-010-87787625 · dengleipumc@163.com
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| National Cancer Center/Cancer Hospital, Chinese Academy of Medical Science and Peking Union Medical College | Beijing, Beijing Municipality, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07443397