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Study identifier: NCT07443072 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Heart Rate Variability and Processed EEG Features as Predictors of Postoperative Outcomes After Cranial Neurosurgery

Condition: Cranial Neurosurgery  ·  Sponsor: Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta

PhaseN/A
Planned participants300
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Patients undergoing cranial neurosurgery face a high-risk postoperative period, particularly during emergence from anesthesia and early recovery in the post-anesthesia care unit (PACU). Standard monitoring provides limited insight into brain and autonomic recovery processes. Heart rate variability (HRV) and processed electroencephalography (pEEG) may offer complementary markers of autonomic and cortical function, with potential to improve early detection of complications and guide individualized care.

This description comes directly from the study's public registry record.

Talk to the study team

Andrea Gentile, MD  ·  + 39 02.2394  ·  andrea.gentile@istituto-besta.it

Marco Gemma, M.D.  ·  02.2394.  ·  marco.gemma@istituto-besta.it

Always discuss trial participation with your own doctor first.

Locations (1)

Fondazione IRCCS Istituto Neurologico Carlo BestaMilan, ItalyRecruiting

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Source record: clinicaltrials.gov/study/NCT07443072