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Study identifier: NCT07441915 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Auditory Sleep Stimulation or Sham in People With Parkinson Disease Mild Cognitive Impairment During Cognitive Training

Condition: Parkinson's Disease · Mild Cognitive Impairment  ·  Sponsor: University of Zurich

PhaseNA
Planned participants50
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

People with Parkinson's disease are at higher risk of cognitive decline, and current treatments cannot fully prevent this. This study explores non-drug ways to support brain function. Intervention: Participants will complete a 5-week cognitive training program at home ("brain fitness"). In addition, they will use a sleep device at night that plays soft sounds to improve deep sleep; Half of the participants will actually receive these sounds (auditory stimulation), while the other half will receive a sham (placebo) version - neither the participants nor the researchers will know the group assignment. Assessments will take place before and after the intervention, and again three months later, including one overnight stay at University Hospital Zurich per assessment. The goal is to find out whether improving deep sleep can boost the benefits of cognitive training and help slow cognitive decline in Parkinson's disease.

This description comes directly from the study's public registry record.

Talk to the study team

Simon J. Schreiner, MD  ·  +41 43 253 24 18  ·  simon.schreiner@usz.ch

Marie Therese Kleinsorge, MD  ·  +41 43 253 13 10  ·  marie.kleinsorge@usz.ch

Always discuss trial participation with your own doctor first.

Locations (1)

University Hospital ZurichZurich, Canton of Zurich, SwitzerlandRecruiting

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Source record: clinicaltrials.gov/study/NCT07441915