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Study identifier: NCT07441824 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Pancreatic Enzyme Replacement in Acute Necrotizing Pancreatitis

Condition: Acute Necrotizing Pancreatitis · Pancreatic Exocrine Insufficiency  ·  Sponsor: Asian Institute of Gastroenterology, India

PhasePhase 3
Planned participants140
Who can joinAll sexes, 18 Years to 60 Years
Healthy volunteersNo

About this study

In this multicenter, double blinded, placebo-controlled, 1:1 parallel group RCT, the investigators propose to evaluate the impact of pancreatic exocrine replacement therapy on patients with acute necrotizing pancreatitis (ANP). The investigators will include patients of 18-60yrs age and both genders with \>50% pancreatic parenchymal necrosis and at least 5% loss of body weight. The primary outcome measure is percent change in body weight at 3 months after enrolment. The intervention will include pancreatic enzyme consisting of 25000 IU of lipase and similar appearing placebo.

This description comes directly from the study's public registry record.

Talk to the study team

Abdul Rasheed, PharmD  ·  +919652104726  ·  abdulrasheedmd1223@gmail.com

Always discuss trial participation with your own doctor first.

Locations (4)

Gauhati Medical CollegeGuwahati, Assam, IndiaRecruiting
Asian Institute of Gastroenterology Hospitals, GachibowliHyderabad, Telangana, IndiaRecruiting
Asian Institute of Gastroenterology, Banjara HillsHyderabad, Telangana, IndiaRecruiting
ILS Hospital, Dum DumKolkata, West Bengal, IndiaRecruiting

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Source record: clinicaltrials.gov/study/NCT07441824