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Study identifier: NCT07441174 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

IN10018 in Combination With RNK08954 for the Treatment of KRASG12D Mutation-Positive Locally Advanced or Metastatic Solid Tumors

Condition: Solid Tumor Cancer · PDAC  ·  Sponsor: InxMed (Shanghai) Co., Ltd.

PhasePhase 1/Phase 2
Planned participants92
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a multicenter, open-label, Phase Ib/II clinical study. The study includes Phase Ib-Dose Exploration Stage and Phase II - Efficacy Exploration and Determination Stage.

This description comes directly from the study's public registry record.

Talk to the study team

Shangyu Chen, Bachelor  ·  86+18752093074  ·  shangyu.chen@inxmed.com

Lily LI, Bachelor  ·  13911551669  ·  lily.li@inxmed.com

Always discuss trial participation with your own doctor first.

Locations (14)

Cancer Hospital Chinese Academy of Medical SciencesBeijing, Beijing Municipality, ChinaNot Yet Recruiting
Fujian Cancer HospitalFuzhou, Fujian, ChinaNot Yet Recruiting
Sun Yat-sen Memorial Hospital, Sun Yat-sen UniversityGuangzhou, Guangdong, ChinaNot Yet Recruiting
The First Affiliated Hospital of Zhengzhou UniversityZhengzhou, Henan, ChinaNot Yet Recruiting
The First Affiliated Hospital of Henan University of Science and TechnologyLuoyang, He, ChinaNot Yet Recruiting
Hunan Cancer HospitalChangsha, Hunan, ChinaNot Yet Recruiting
Affiliated Drum Tower Hospital, Medical School of Nanjing UniversityNanjing, Jiangsu, ChinaNot Yet Recruiting
Jiangsu Province HospitalNanjing, Jiangsu, ChinaNot Yet Recruiting
The First Affiliated Hospital of China Medical UniversityShengyang, Liaoning, ChinaNot Yet Recruiting
Shandong Cancer HospitalJinan, Shandong, ChinaNot Yet Recruiting
Renji Hospital Affiliated to Shanghai Jiao Tong University School of MedicineShanghai, Shanghai Municipality, ChinaNot Yet Recruiting
The First Affiliated Hospital of Xi'an Jiaotong UniversityXi’an, Shanxi, ChinaNot Yet Recruiting

+ 2 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07441174