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Study identifier: NCT07440225 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-002)

Condition: Macular Degeneration · Age-Related Macular Degeneration · Choroidal Neovascularization  ·  Sponsor: EyeBiotech Ltd.

PhasePhase 2/Phase 3
Planned participants960
Who can joinAll sexes, 50 Years to no upper limit
Healthy volunteersNo

About this study

Researchers are looking for new ways to treat neovascular age-related macular degeneration (NVAMD). Available standard (usual) treatments for NVAMD, such as aflibercept, may not work for every person. Researchers want to learn if a trial medicine called tiespectus (also called MK-8748 or EYE201) can treat NVAMD. The goal of this trial is to learn if tiespectus works as well as aflibercept to treat NVAMD.

This description comes directly from the study's public registry record.

Talk to the study team

Toll Free Number  ·  1-888-577-8839  ·  Trialsites@msd.com

Always discuss trial participation with your own doctor first.

Locations (91)

Research Network Arizona / Retina Macula Institute of ArizonaScottsdale, Arizona, United StatesRecruiting
Retina Center of ArkansasFayetteville, Arkansas, United StatesRecruiting
Retina Partners of Northwest Arkansas, PLLCSpringdale, Arkansas, United StatesRecruiting
Global Research Management, Inc.Glendale, California, United StatesRecruiting
Retinal Consultants Medical Group (Site 024)Modesto, California, United StatesRecruiting
Retina Consultants of Southern California (Site 043)Redlands, California, United StatesRecruiting
Retinal Consultants Medical Group (Site 020)Sacramento, California, United StatesRecruiting
Retinal Consultants Medical Group (Site 022)Sacramento, California, United StatesRecruiting
Florida Eye Clinic (Site 130)Altamonte Springs, Florida, United StatesRecruiting
Retina Group of Florida (Site 070)Fort Lauderdale, Florida, United StatesRecruiting
Vitreo Retinal AssociatesGainesville, Florida, United StatesRecruiting
Fort Lauderdale Eye Institute (Site 042)Plantation, Florida, United StatesRecruiting

+ 79 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07440225