Condition: Urothelial Carcinoma (UC) · Sponsor: Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
This study is an open-label, single-arm, interventional clinical trial designed to investigate the safety of ⁶⁸Ga/¹⁷⁷Lu-BRP-020063 in patients with advanced metastatic solid tumors; to evaluate the pharmacokinetics, biodistribution, and radiation dosimetry of ¹⁷⁷Lu-BRP-020063 in patients with metastatic solid tumors; and to preliminarily explore its therapeutic efficacy. The study plans to enroll 10 patients to receive ⁶⁸Ga-BRP-020063 PET/CT imaging, among whom 5 patients positive for ⁶⁸Ga-BRP-020063 will be selected to receive a low dose of ¹⁷⁷Lu-BRP-020063. The results of this study will provide a basis for the design of subsequent studies involving higher doses of ¹⁷⁷Lu-BRP-020063.
This description comes directly from the study's public registry record.
Yan Xing, Dr. · +862163246311 · xy.1@163.com
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| Shanghai General Hospital | Shanghai, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07439120