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Study identifier: NCT07438782 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

First Time in Human (FTIH) Study to Investigate the Safety and Preliminary Activity of GSK5533524 Alone or in Combination in Adult Participants With Advanced Solid Tumors

Condition: Neoplasms  ·  Sponsor: GlaxoSmithKline

PhasePhase 1
Planned participants97
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to investigate a new drug GSK5533524 in adults with certain advanced cancers to find a safe dose and learn how well people tolerate it, so researchers can choose the best dose for the next stage of testing. The study will also check whether the drug can shrink tumours or slow cancer growth, monitor how the body absorbs and breaks down the drug, and look for any immune reactions that the body might develop against the treatment.

This description comes directly from the study's public registry record.

Talk to the study team

US GSK Clinical Trials Call Center  ·  877-379-3718  ·  GSKClinicalSupportHD@gsk.com

EU GSK Clinical Trials Call Center  ·  +44 (0) 20 89904466  ·  GSKClinicalSupportHD@gsk.com

Always discuss trial participation with your own doctor first.

Locations (16)

GSK Investigational SitePhiladelphia, Pennsylvania, United StatesRecruiting
GSK Investigational SiteSan Antonio, Texas, United StatesRecruiting
GSK Investigational SiteToronto, Ontario, CanadaRecruiting
GSK Investigational SiteMontreal, Quebec, CanadaRecruiting
GSK Investigational SiteMontreal, Quebec, CanadaRecruiting
GSK Investigational SiteHelsinki, FinlandRecruiting
GSK Investigational SiteSaitama, JapanRecruiting
GSK Investigational SiteShizuoka, JapanRecruiting
GSK Investigational SiteTokyo, JapanRecruiting
GSK Investigational SiteTokyo, JapanRecruiting
GSK Investigational SiteBarcelona, SpainRecruiting
GSK Investigational SiteMadrid, SpainRecruiting

+ 4 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07438782