Condition: EBV-DNA Viremia · Post-Transplant Lymphoproliferative Disorder · Sponsor: Daihong Liu
This exploratory clinical study focuses on the use of EBV-AST cell infusion for treating EBV-DNA viremia following allogeneic hematopoietic stem cell transplantation (Allo-HSCT). The study aims to determine the maximum tolerated dose (MTD) or optimal biological dose (OBD) of EBV-AST cells and assess their safety, tolerability, and preliminary efficacy in treating EBV-DNA viremia. The study will involve a 3+3 dose escalation design to evaluate three different dosages of EBV-AST cell infusion. The study is expected to provide important insights into the clinical application of cell-based therapies for EBV infections.
This description comes directly from the study's public registry record.
Daihong Liu · +8613681171597 · daihongrm@163.com
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| Chinese PLA General Hospital | Beijing, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07438067