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Study identifier: NCT07435337 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Effect of Nalbuphine Versus Fentanyl on Hemdoynamic Effects of Laryngoscopy

Condition: Laryngoscopy · Hemodynamic Changes  ·  Sponsor: Rawalpindi Institute of Cardiology

PhasePhase 4
Planned participants98
Who can joinAll sexes, 40 Years to 60 Years
Healthy volunteersYes

About this study

Participants will undergo routine pre-operative evaluation. An intravenous line will be placed in the recovery area. On arrival in the operating room, standard monitoring (blood pressure, heart rate, oxygen saturation, ECG, breathing monitor, and temperature) will be applied. A central venous catheter and an arterial line will be inserted under local anesthesia using sterile technique. Before anesthesia induction, patients will receive premedication including midazolam and an opioid pain-relief injection given slowly through the vein. General anesthesia will then be induced with etomidate. After adequate sedation, a muscle relaxant (atracurium) will be administered, and the patient will be ventilated with 100% oxygen using a face mask. The breathing tube will then be inserted and correct placement confirmed. During surgery, anesthesia will be maintained with oxygen, sevoflurane gas, and a continuous atracurium infusion. Hemodynamic parameters such as heart rate and blood pressure will be monitored throughout the peri-intubation and intraoperative period.

This description comes directly from the study's public registry record.

Talk to the study team

Ayemon Principal Investigator, MBBS  ·  +923211579066  ·  ayemonfatima@gmail.com

Always discuss trial participation with your own doctor first.

Locations (1)

Deparment of Anesthesia, Rawalpindi Institute of Cardiology, RawalpindiRawalpindi, Punjab Province, PakistanRecruiting

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Source record: clinicaltrials.gov/study/NCT07435337