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Study identifier: NCT07432932 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Precision Medicine Approaches for Neoadjuvant Therapy in High-risk Sarcoma Patients

Condition: Sarcoma · Sarcoma, Leiomyo-, Adult · Sarcoma, Synovial, Adult  ·  Sponsor: Royal Marsden NHS Foundation Trust

PhaseN/A
Planned participants800
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a cohort study aimed at developing a stratified medicine approach for personalised neoadjuvant chemotherapy (NCT) in high-risk soft tissue sarcoma (STS) patients with dedifferentiated liposarcoma (DDLPS), leiomyosarcoma (LMS), synovial sarcoma (SS), vascular sarcomas, malignant peripheral nerve sheath tumour (MPNST) or other subtypes. It comprises of both retrospective and prospective tissue collection from patients advancing directly to surgery (control group) and patients receiving NCT and surgery.

This description comes directly from the study's public registry record.

Talk to the study team

Stephanie Elston, MSc  ·  02073528171  ·  PANTHRS.Trial@rmh.nhs.uk

Thuy-Giang Nguyen, BSc  ·  02073528171  ·  PANTHRS.Trial@rmh.nhs.uk

Always discuss trial participation with your own doctor first.

Locations (1)

The Royal Marsden HospitalLondon, United KingdomRecruiting

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Source record: clinicaltrials.gov/study/NCT07432932