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Study identifier: NCT07432204 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Therapeutic Music Listening in Post Stroke Patients.

Condition: Post Stroke · Anxiety · Depression  ·  Sponsor: Istituti Clinici Scientifici Maugeri SpA

PhaseNA
Planned participants132
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Numerous studies have highlighted how individualized music listening favors motor, cognitive, and emotional recovery in post-stroke patients, stimulating neuroplasticity and cerebral connectivity. However, gaps persist regarding the standardization of protocols and the neural mechanisms involved. This study aims to bridge these gaps with a rigorous scientific approach, integrating clinical assessments and neuroimaging. This is a multicenter randomized controlled single-blind trial. Subjects will be allocated into 2 groups: an experimental group subjected to a 4-week intervention of daily Therapeutic Music Listening sessions (Raglio, 2023) in addition to conventional therapeutic interventions (standard care), and a control group subjected solely to conventional therapeutic interventions (standard care). A follow-up is scheduled for one month after the conclusion of treatment. The study duration is 24 months and the screening phase will be continuous until the conclusion of planned recruitment. Primary objective of the study is to evaluate the efficacy of Therapeutic Music Listening (TML) on anxiety in post-stroke patients. Secondary objective of the study is to investigate other possible effects on depression, quality of life, cognitive aspects (specifically attention and memory), and on connectivity via functional Magnetic Resonance Imaging (fMRI). Primary endpoint is the reduction of anxiety. Secondary endpoint is the improvement in depression, quality of life, cognitive…

This description comes directly from the study's public registry record.

Talk to the study team

Alfredo Raglio  ·  +39 3387291944  ·  alfredo.raglio@icsmaugeri.it

Always discuss trial participation with your own doctor first.

Locations (1)

Fondazione Salvatore Maugeri I.R.C.C.S.Pavia, ItalyRecruiting

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Source record: clinicaltrials.gov/study/NCT07432204