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Study identifier: NCT07431606 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Duloxetine in Inflammatory Bowel Diseases

Condition: Inflammatory Bowel Diseases  ·  Sponsor: University of Pennsylvania

PhasePhase 2
Planned participants32
Who can joinAll sexes, 24 Years to no upper limit
Healthy volunteersNo

About this study

This open-label, prospective, single-arm pilot study investigates the use of duloxetine, a central neuromodulator, for improving psychological distress and functional impairment in adults with inflammatory bowel disease (IBD). The study focuses on patient-reported outcomes related to anxiety, depression, and IBD-related disability, aiming to assess feasibility, tolerability, and preliminary efficacy in modulating gut-brain axis symptoms and disease-related functional impairments in life

This description comes directly from the study's public registry record.

Talk to the study team

Chung Tse, MD  ·  2153498222  ·  Chung.Tse@Pennmedicine.upenn.edu

Maureen DeMarshall, BSN, RN  ·  2153498546  ·  demarshm@pennmedicine.upenn.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of PennsylvaniaPhiladelphia, Pennsylvania, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07431606