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Study identifier: NCT07430969 Synced from ClinicalTrials.gov · July 29, 2026
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The Effect of Muscle Stimulation and Amino Acid Intake on Protein Metabolism During Critical Illness

Condition: Muscle Wasting in Critically Ill  ·  Sponsor: Wageningen University

PhaseNA
Planned participants30
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this clinical trial is to study how whole-body electrical stimulation combined with amino acid intake affects muscle health in ventilated ICU patients. The main questions to answer are: * Does electrostimulation improve the balance of muscle protein in ICU patients? * Does combining electrostimulation with amino acid help build muscle and prevent muscle loss? Researchers will compare three groups of patients: 1. Sham electrostimulation (no current applied) + the standard nutrition 2. Electrostimulation + the standard nutrition 3. Electrostimulation + a 20g amino acid bolus Participants will: * Receive either real or sham electrostimulation * Get their standard nutrition or a 20g amino acid bolus * Have marked amino acids given through an IV * Have blood samples taken to measure the amino acids and glucose in the blood * Undergo ultrasound of the upper arm to measure the blood flow

This description comes directly from the study's public registry record.

Talk to the study team

Marlou Dirks, PhD  ·  +31 317 480 100  ·  marlou.dirks@wur.nl

Always discuss trial participation with your own doctor first.

Locations (1)

Hospital Gelderse ValleiEde, NetherlandsRecruiting

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Source record: clinicaltrials.gov/study/NCT07430969