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Study identifier: NCT07430761 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

ET Stigma Response to Tremor Suppression

Condition: Action Tremor · Stigma, Social  ·  Sponsor: University of Texas Southwestern Medical Center

PhaseN/A
Planned participants220
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Essential Tremor (ET) is prevalent, affecting approximately 3% of the adult population. Involuntary shaking of the hands during action is a prominent feature, interfering with feeding and writing and other manual tasks. The involuntary movement is visible to observers, some of whom misinterpret the shakiness as manifestation of anxiety or instability, while some other observers attribute it to alcohol or drug use. The psychological effects of resulting stigma on quality of life for people with ET can rival the physical difficulties caused by the condition. For this study, we propose to measure 1 year after effective tremor suppression following thalamotomy with high intensity focused ultrasound changes from baseline in psychological distress and social dysfunction related to ET stigma, and to correlate change from baseline with improvement in functional status related to tremor and in objective measures of tremor severity. We hope to discover that ET stigma is largely reversible when tremor is effectively treated, and we aim to learn what degree of tremor suppression correlates with substantial psychological relief. We will also determine if ET stigma is predominantly helped by unilateral dominant-hand treatment, or if the second side treatment is necessary to accomplish most benefit.

This description comes directly from the study's public registry record.

Talk to the study team

Padraig E O'Suilleabhain, MD  ·  2146482943  ·  padraig.osuilleabhain@utsouthwestern.edu

Padraig E O'Suilleabhain  ·  2146482943

Always discuss trial participation with your own doctor first.

Locations (1)

University of Texas Soouthwestern Medical CenterDallas, Texas, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07430761