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Study identifier: NCT07429461 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Clinical Study of SYNCAR-100 in the Treatment of Relapsed/Refractory Acute B-Lymphoblastic Leukemia

Condition: B-Cell Acute Lymphoblastic Leukemia  ·  Sponsor: Zhejiang University

PhaseEARLY_Phase 1
Planned participants16
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

The purpose of this study is to assess the safety, tolerability, and preliminary efficacy of SYNCAR-100 in patients with CD19-positive relapsed or refractory B-cell acute lymphoblastic leukemia (R/R B-ALL). Participants who have signed the informed consent form will undergo screening against the inclusion and exclusion criteria. Eligible participants will receive study drug administration once weekly for a total of four doses, followed by a 1-year safety and efficacy follow-up observation period. After the completion of the study, long-term follow-up may be required for participants to monitor their health and survival status until 15 years post-treatment, or until the occurrence of patient death, loss to follow-up, or withdrawal of consent.

This description comes directly from the study's public registry record.

Talk to the study team

He Huang, MD  ·  13605714822  ·  hehuangyu@126.com

Yongxian Hu, MD  ·  057187233772  ·  huyongxian2000@aliyun.com

Always discuss trial participation with your own doctor first.

Locations (1)

The first affiliated hospital of medical college of zhejiang universityHangzhou, Zhejiang, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07429461