Condition: Stroke · Sponsor: Centre Hospitalier Universitaire Vaudois
High-dose, high-intensity (HDHI) neurorehabilitation has shown promise for improving functional outcomes after acquired brain injury (ABI), yet its feasibility and impact across different stages of care and real-world clinical settings remain insufficiently understood. The SwissNeuroRehab (SNR) initiative, bringing together Swiss rehabilitation centres to develop and evaluate innovative, technology-supported models of neurorehabilitation, provides the broader framework within which this study is conducted. Within this framework, a structured HDHI therapy pathway supported by CE-marked digital neurorehabilitation tools has been developed for delivery across inpatient, outpatient, and home environments in Switzerland. This multicentre, non-randomised interventional feasibility study evaluates the feasibility and preliminary clinical effects of implementing this HDHI rehabilitation pathway for adults with stroke in subacute and chronic stages. Participants will receive approximately 300 minutes per week of active, technology-supported training in addition to standard rehabilitation care, following an individually tailored pathway across settings. Standardised clinical assessments, patient-reported outcomes, documentation of rehabilitation procedures, and socioeconomic measures will be collected at baseline, discharge, and follow-up timepoints up to 12-15 months post-enrollment. The primary aim of the study is to assess the feasibility of the HDHI intervention within routine …
This description comes directly from the study's public registry record.
Olivier Bill, MD · +41 0213141260 · olivier.bill@chuv.ch
Andrea Serino, Prof. · +41 21 314 3996 · andrea.serino@chuv.ch
Always discuss trial participation with your own doctor first.
| Lake Lucerne Institute | Vitznau, Canton of Lucerne, Switzerland | Not Yet Recruiting |
| Klinik Valens | Valens, Canton of St. Gallen, Switzerland | Recruiting |
| Centre hospitalier universitaire Vaudois | Lausanne, Canton of Vaud, Switzerland | Recruiting |
| Swiss Réhabilitation Sàrl | Sullens, Canton of Vaud, Switzerland | Recruiting |
| Universitätspital Zürich | Zurich, Canton of Zurich, Switzerland | Not Yet Recruiting |
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Source record: clinicaltrials.gov/study/NCT07427511