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Study identifier: NCT07426848 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

OT SMILE: Occupational Therapy Group Intervention for Primary Brain Tumour Patients

Condition: Primary Brain Tumour · Glioblastoma · Brain Neoplasms  ·  Sponsor: Royal College of Surgeons, Ireland

PhaseNA
Planned participants96
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

People diagnosed with primary brain tumours often experience significant symptoms such as fatigue, cognitive changes, anxiety, and reduced ability to carry out everyday activities. These symptoms may be related to the tumour itself or to ongoing systemic anti-cancer treatment. In Ireland, access to structured rehabilitation and symptom management programmes for this population is limited. The OT SMILE study is evaluating whether a structured occupational therapy-led group programme can improve quality of life and daily functioning in adults with primary brain tumours receiving active treatment. Participants attending Beaumont Hospital who meet eligibility criteria and provide informed consent will be randomly assigned (like flipping a coin) to one of two groups: A six-week occupational therapy group programme (OT SMILE), or Usual care, consisting of written lifestyle management information. The OT SMILE programme consists of six weekly 90-minute group sessions delivered by occupational therapists. Sessions focus on fatigue management, activity modification, cognitive strategies, relaxation techniques, goal setting, exercise, nutrition, and peer support. Participants in both groups will complete questionnaires before the programme begins and again after six weeks. These questionnaires measure quality of life, fatigue, and daily functioning. The main goal of the study is to determine whether the occupational therapy group programme improves health-related quality of life…

This description comes directly from the study's public registry record.

Talk to the study team

Caoilfhionn O Donovan  ·  +35318093000  ·  caoilfhionnodonovan@rcsi.ie

Always discuss trial participation with your own doctor first.

Locations (1)

Beaumont RCSI Cancer CentreDublin, Beaumont, IrelandRecruiting

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Source record: clinicaltrials.gov/study/NCT07426848