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Study identifier: NCT07426419 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

An AAV Gene Therapy Trial of AFTX-201 in Adults With BAG3-Associated Dilated Cardiomyopathy (DCM)

Condition: Dilated Cardiomyopathy (DCM) · BAG3 Mutation Associated Dilated Cardiomyopathy  ·  Sponsor: Affinia Therapeutics

PhasePhase 1/Phase 2
Planned participants22
Who can joinAll sexes, 18 Years to 55 Years
Healthy volunteersNo

About this study

This is a Phase 1/2, open-label, dose-exploration and dose-expansion, clinical trial evaluating the safety, tolerability, pharmacodynamics, and preliminary efficacy of a single intravenous infusion of AFTX-201 in adults with dilated cardiomyopathy caused by a BAG3 gene mutation

This description comes directly from the study's public registry record.

Talk to the study team

Clinical Trials Information  ·  (617) 430-7817  ·  clinicaltrials@affiniatx.com

Always discuss trial participation with your own doctor first.

Locations (3)

University of Miami Hospital and ClinicsMiami, Florida, United StatesRecruiting
St. Lukes HospitalKansas City, Missouri, United StatesRecruiting
Houston Methodist HospitalHouston, Texas, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07426419