Condition: Stargardt Disease · Stargardt Macular Dystrophy · Stargardt-like Macular Dystrophy · Sponsor: Astellas Pharma Global Development, Inc.
Macular dystrophies are a group of inherited eye conditions that affect the macula. The macula is in the center of the retina, the light sensitive part at the back of the eye. In people with macular dystrophies, some of the cells in the macula gradually stop working and may die over time. This leads to vision loss in the center of the eye. Side vision (peripheral vision) is mostly unaffected. Stargardt disease (STGD) is a type of macular dystrophy which is caused by 1 faulty gene (ABCA4). Vision loss most typically happens in childhood, but many people do not develop it until they are adults. As well as STGD, there are other macular dystrophies that look very similar to STGD but that are caused by many other different genes. Together, STGD and STGD-like conditions can be called STGD-type macular dystrophies. This is because they look the same clinically and have similar symptoms. Since different genes can cause these conditions, genetic testing is the only way to be sure which specific condition a person has. In this study, researchers want to learn if the disease progresses in a similar way in people with STGD and STGD-like macular dystrophies. People taking part in the study will continue to manage their condition, as agreed with their own doctor. People will visit their clinic every 6 months to have various standard eye tests and imaging. The information collected will include questions about people's wellbeing, general health, medication and supplements taken, and daily …
This description comes directly from the study's public registry record.
Astellas Pharma Global Development, Inc. · 800-888-7704 · Astellas.registration@astellas.com
Always discuss trial participation with your own doctor first.
| Associated Retina Consultants | Phoenix, Arizona, United States | Recruiting |
| Stanford University School of Medicine | Palo Alto, California, United States | Recruiting |
| University of California Health - UC Davis | Sacramento, California, United States | Recruiting |
| University of Illinois Chicago - UI Health | Chicago, Illinois, United States | Recruiting |
| University of Michigan Health - Kellogg Eye Center | Ann Arbor, Michigan, United States | Recruiting |
| Deep Blue Retina | Southaven, Mississippi, United States | Recruiting |
| Duke Eye Center | Durham, North Carolina, United States | Recruiting |
| Casey Eye Institute - Oregon Health & Science University | Portland, Oregon, United States | Recruiting |
| Wills Eye Physicians - Mid Atlantic Retina | Philadelphia, Pennsylvania, United States | Recruiting |
| University of Pittsburgh Medical Center | Pittsburgh, Pennsylvania, United States | Recruiting |
| Retina Foundation of the Southwest | Dallas, Texas, United States | Recruiting |
| University of Utah Health - John A Moran Eye Center | Salt Lake City, Utah, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07425574