● Recruiting

A Study to Evaluate the Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of RO7823653 in Participants With Diabetic Macular Edema (DME)

Condition: Diabetic Macular Edema · Sponsor: Genentech, Inc.

PhasePhase 1

Planned participants93

Who can joinAll sexes, 18 Years to no upper limit

Healthy volunteersNo

About this study

The purpose of this study is to evaluate the safety, tolerability, Pharmacodynamics (PD), and Pharmacokinetics (PK) of multiple doses of RO7823653 in participants with DME, administered by intravitreal (IVT) injection as monotherapy and co-administered with faricimab.

This description comes directly from the study's public registry record.

Talk to the study team

Reference Study ID Number GR46431 https://forpatients.roche.com/ No attachments to email below. · 888-662-6728 (U.S. and Canada) · global-roche-genentech-trials@gene.com

Fastest response: use the inquiry form. https://www.gene.com/contact-us/submit-medical-inquiry

Always discuss trial participation with your own doctor first.

Locations (10)

Associated Retina Consultants - Peoria - DocTrials - PPDS	Peoria, Arizona, United States	Recruiting
Retina-Vitreous Associates Medical Group	Beverly Hills, California, United States	Recruiting
Bay Area Retina Specialists Medical Group - Vestrum - PPDS	Walnut Creek, California, United States	Recruiting
Retina Vitreous Associates of Florida	St. Petersburg, Florida, United States	Recruiting
Erie Retina Research, LLC - 300 State St	Erie, Pennsylvania, United States	Recruiting
Charles Retina Institute	Germantown, Tennessee, United States	Recruiting
Retina Research Institute of Texas	Abilene, Texas, United States	Recruiting
Austin Clinical Research, LLC	Austin, Texas, United States	Recruiting
Retina Consultants of Texas Westover Hills Retina Center	San Antonio, Texas, United States	Recruiting
Piedmont Eye Center	Lynchburg, Virginia, United States	Recruiting

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Source record: clinicaltrials.gov/study/NCT07425522