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Study identifier: NCT07425080 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

HELIOS Advanced: Human Oocyte Illumination to Enhance Development

Condition: IVF Outcomes  ·  Sponsor: Columbia University

PhaseNA
Planned participants270
Who can joinFemale, 18 Years to 48 Years
Healthy volunteersYes

About this study

Oocytes need a lot of energy to complete meiosis and fertilize successfully. As women get older, the "power plants" of the cells (called mitochondria) don't work as well. This makes it harder for eggs and embryos to develop normally. One possible way to help is with a gentle light treatment called photobiomodulation (PBM). This uses a special type of red light that boosts energy production in cells and helps them stay healthy. This study will test whether adding this light treatment during in vitro fertilization (IVF) can improve embryo growth and pregnancy outcomes.

This description comes directly from the study's public registry record.

Talk to the study team

Samuel Zev Williams, MD, PhD  ·  646-756-8282  ·  zw2421@cumc.columbia.edu

Laura C Gemmell, MD, MSc  ·  646-756-8282  ·  lg3094@cumc.columbia.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Columbia University Fertility CenterNew York, New York, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07425080