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Study identifier: NCT07424807 Synced from ClinicalTrials.gov · July 29, 2026
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Comparison of Two Needle Agitation Strategies in Endobronchial Ultrasound-guided Transbronchial Needle Aspiration (EBUS-TBNA) for Diagnostic Yield

Condition: Mediastinal Lymphadenopathy  ·  Sponsor: Phan Quang Hieu

PhaseNA
Planned participants180
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this clinical trial is to learn whether the number of needle agitations during endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) affects diagnostic yield in patients with enlarged mediastinal lymph nodes. The study will also evaluate tissue sample quality and the safety of different needle agitation strategies. The main questions it aims to answer are: Does the number of needle agitations improve diagnostic yield? Does a higher number of needle agitations increase tissue core length and specimen adequacy? Are there differences in procedure-related complications between the two needle agitation strategies? Researchers will compare two needle agitation strategies during EBUS-TBNA to see if one approach provides better diagnostic performance, improved sample quality, and similar procedural safety. Participants will: * Undergo EBUS-TBNA as part of their clinical evaluation * Be randomly assigned to one of two needle agitation strategies * Have tissue samples measured for core length and assessed for diagnostic adequacy * Be monitored for procedure-related complications

This description comes directly from the study's public registry record.

Talk to the study team

Hieu Q Phan, MD, M.Sc.  ·  +84907718538  ·  hieu.pq@umc.edu.vn

Always discuss trial participation with your own doctor first.

Locations (1)

University Medical Center Ho Chi Minh CityHo Chi Minh City, Ho Chi Minh, VietnamRecruiting

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Source record: clinicaltrials.gov/study/NCT07424807