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Study identifier: NCT07423650 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Continous Infusion of Nefopam for Patients Undergoing Pancreatoduodenectomy

Condition: Pancreatoduodenectomy · Pain Management · Opioid Analgesia  ·  Sponsor: Iuliu Hatieganu University of Medicine and Pharmacy

PhasePhase 4
Planned participants93
Who can joinAll sexes, 18 Years to 80 Years
Healthy volunteersNo

About this study

The goal of this clinical trial is to determine whether continuous nefopam administration, as part of a multimodal analgesia strategy, reduces opioid consumption and improves patient satisfaction after pancreatoduodenectomy. The main questions are: Does nefopam administration reduce opioid consumption after pancreatoduodenectomy? Does nefopam administration reduce postoperative pain levels after pancreatoduodenectomy? Researchers will compare two other analgesic strategies, namely continuous lidocaine infusion and epidural analgesia, to assess whether they lead to better outcomes. Participants will complete the QoR-15 questionnaire and report their pain levels at predefined time points before and after surgery.

This description comes directly from the study's public registry record.

Talk to the study team

Andrei O Mitre  ·  +40724275556  ·  andrei.otto.mitre@elearn.umfcluj.ro

Always discuss trial participation with your own doctor first.

Locations (1)

Prof. O. Fodor Regional Institute of Gastroenterology and HepatologyCluj-Napoca, Cluj, RomaniaRecruiting

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Source record: clinicaltrials.gov/study/NCT07423650