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Study identifier: NCT07421258 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Retrospective Study to Evaluate Treat-to-Target and Disease Modification in Adult Participants With Crohn's Disease and Ulcerative Colitis in Real World Setting

Condition: Crohn's Disease · Ulcerative Colitis  ·  Sponsor: AbbVie

PhaseN/A
Planned participants2000
Who can joinAll sexes, 20 Years to no upper limit
Healthy volunteersNo

About this study

Inflammatory Bowel Disease (IBD), encompassing Crohn's Disease (CD) and Ulcerative Colitis (UC), is a chronic, relapsing, and often disabling condition characterized by inflammation of the gastrointestinal tract. A treat-to-target strategy (T2T) is recommended by international guidelines to optimize long-term outcomes in IBD. The purpose of this study is to describe the real-life implementation of T2T in IBD worldwide and the association between using a T2T strategy and disease outcomes. This is a multi-country, observational, retrospective (non-interventional) study with a cross-sectional component based upon a sample of adult participants with IBD. All objectives will be assessed for IBD and then for CD/UC separately. Primary and secondary objectives will be assessed for the overall population over the 24 months study period. As this is an observational study, enrolled participants will be managed and followed up according to the standard practice. Retrospective chart review over the 24-months from date of inclusion will allow us to collect the variables of interest by using an e-CRF. There will be no additional burden for participants in this trial. Study visits will not be required as this is a retrospective chart review.

This description comes directly from the study's public registry record.

Talk to the study team

Colla Cunneen  ·  708-650-3696  ·  colla.cunneen@abbvie.com

Always discuss trial participation with your own doctor first.

Locations (4)

Chongqing General Hospital /ID# 282777Chongqing, Chongqing Municipality, ChinaRecruiting
Centre Hospitalier Universitaire de Nîmes - Hôpital Universitaire Carémeau /ID# 282775Nîmes, Gard, FranceNot Yet Recruiting
Centre Hospitalier Régional Universitaire de Nancy - Hôpitaux de Brabois /ID# 280265Vandœuvre-lès-Nancy, Meurthe-et-Moselle, FranceNot Yet Recruiting
CHU Amiens-Picardie Site Sud /ID# 280263Amiens, Somme, FranceNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT07421258