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Study identifier: NCT07419841 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Phase 1 Study of the Safety and Tolerability of CTX-10726

Condition: Gastroesophageal Cancer (GC) · Hepatocellular Carcinoma (HCC) · Endometrial Cancer  ·  Sponsor: Compass Therapeutics

PhasePhase 1
Planned participants70
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a Phase 1, open-label, first-in-human study of CTX-10726 monotherapy in patients with metastatic or locally advanced malignancies. The study will be conducted in 2 Cohorts: Cohort 1 Dose Escalation and Cohort 2 Dose Expansion.

This description comes directly from the study's public registry record.

Talk to the study team

Sarah Pilgrim  ·  617-500-8099  ·  ctx-10726-001@compasstherapeutics.com

Talia Fountain  ·  617-500-8099  ·  ctx-10726-001@compasstherapeutics.com

Always discuss trial participation with your own doctor first.

Locations (6)

Dana Farber Cancer InstituteBoston, Massachusetts, United StatesNot Yet Recruiting
Nebraska Cancer SpecialistsOmaha, Nebraska, United StatesRecruiting
START New YorkLake Success, New York, United StatesRecruiting
UPMC Hillman Cancer CenterPittsburgh, Pennsylvania, United StatesRecruiting
Prisma Health Cancer InstituteGreenville, South Carolina, United StatesRecruiting
SCRI Oncology PartnersNashville, Tennessee, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07419841