← Eichor
Study identifier: NCT07419295 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Clinical Trial of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) to Treat Urothelial Cancer (MK-2870-031)

Condition: Bladder Cancer  ·  Sponsor: Merck Sharp & Dohme LLC

PhasePhase 3
Planned participants590
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Researchers are looking for new ways to treat locally advanced or metastatic urothelial cancer (UC). Current treatments for locally advanced or metastatic UC include chemotherapy, immunotherapy, and targeted therapy. Researchers want to know if giving sacituzumab tirumotecan (sac-TMT), the trial medicine, can treat locally advanced or metastatic UC that got worse after certain treatments. The goal of this trial is to learn if people who receive sac-TMT live longer than those who receive certain non-platinum chemotherapies.

This description comes directly from the study's public registry record.

Talk to the study team

Toll Free Number  ·  1-888-577-8839  ·  Trialsites@msd.com

Always discuss trial participation with your own doctor first.

Locations (71)

Munson Medical Center ( Site 0812)Traverse City, Michigan, United StatesRecruiting
TriHealth Cancer Institute-Good Samaritan Hospital ( Site 0822)Cincinnati, Ohio, United StatesRecruiting
The West Clinic, P.C. ( Site 0791)Germantown, Tennessee, United StatesRecruiting
Thompson Cancer Survival Center ( Site 0803)Knoxville, Tennessee, United StatesRecruiting
Asociacion de Beneficencia Hospital Sirio Libanes ( Site 0003)Ciudad Autonoma de Buenos Aires, Buenos Aires, ArgentinaRecruiting
Instituto Alexander Fleming ( Site 0002)Ciudad Autónoma de Buenos Aires, Buenos Aires, ArgentinaRecruiting
Instituto de Oncologia de Rosario ( Site 0005)Rosario, Santa Fe Province, ArgentinaRecruiting
Macquarie University ( Site 0031)Macquarie, New South Wales, AustraliaRecruiting
Mater Hospital Brisbane ( Site 0032)South Brisbane, Queensland, AustraliaRecruiting
Cliniques Universitaires Saint-Luc ( Site 0062)Brussels, Bruxelles-Capitale, Region de, BelgiumRecruiting
AZ Maria Middelares ( Site 0063)Ghent, Oost-Vlaanderen, BelgiumRecruiting
UZ Gent ( Site 0064)Ghent, Oost-Vlaanderen, BelgiumRecruiting

+ 59 more locations — full list on the registry record.

Follow this study

Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.

We email about this public record only. Unsubscribe anytime with one click. Never medical advice.

Is this your study? This page was generated automatically from the public registry record. Sponsors can claim it — free — to add branding and verified contact routing. Claim this page →

This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.

Source record: clinicaltrials.gov/study/NCT07419295