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Study identifier: NCT07417358 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Single-Stapled Technique for Colorectal Anastomosis

Condition: Colorectal Cancer · Colorectal Anastomosis · Anastomotic Leakage  ·  Sponsor: Umeå University

PhaseN/A
Planned participants500
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this observational multicenter study is to evaluate the safety and feasibility of a single-stapled technique (SST) for colorectal anastomosis and to explore whether this technique is associated with a reduced rate of anastomotic leakage compared with the conventional double-stapled technique (DST). The study includes adult patients undergoing planned left-sided colorectal resection with colorectal anastomosis, including sigmoid resection, left hemicolectomy, or partial mesorectal excision (PME), for benign or malignant disease. The main questions it aims to answer are: What is the rate of anastomotic leakage within 90 days after surgery in patients operated with the single-stapled technique? Is the single-stapled technique feasible and safe across different surgical approaches (open, laparoscopic, and robot-assisted surgery) in a multicenter setting? Furthermore, outcomes after single-stapled anastomosis will be compared with a retrospective cohort of patients operated with the conventional double-stapled technique to explore potential differences in anastomotic leakage rates and postoperative complications. Participants will receive standard surgical care as determined by the treating surgical team. Patients included in the prospective part of the study will undergo colorectal anastomosis using the single-stapled technique as part of routine clinical practice. Data on perioperative variables, postoperative complications (including anastomotic leakage graded…

This description comes directly from the study's public registry record.

Talk to the study team

Oskar Grahn, MD, PhD  ·  +46907850000  ·  oskar.grahn@umu.se

Always discuss trial participation with your own doctor first.

Locations (5)

Östra Sahlgrenska University HospitalGothenburg, SwedenRecruiting
Sunderby HospitalLuleå, SwedenRecruiting
Skåne University HospitalMalmö, SwedenRecruiting
Surgical Centre, Umeå University HospitalUmeå, SwedenRecruiting
Uppsala University HospitalUppsala, SwedenRecruiting

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Source record: clinicaltrials.gov/study/NCT07417358