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Study identifier: NCT07416968 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Randomized Controlled Trial Comparing Low Dose Tadalafil Versus Solifenacin For Management of Overactive Bladder in Women: Multicenter Egyptian National Study

Condition: Overactive Bladder (OAB) · Overactive Bladder Syndrome  ·  Sponsor: Mansoura University

PhasePhase 4
Planned participants480
Who can joinFemale, 18 Years to 75 Years
Healthy volunteersNo

About this study

Researchers are studying two medicines to see which works better for women with overactive bladder (OAB). OAB causes sudden urges to urinate, frequent bathroom trips, and sometimes leakage. Women who join the study will be randomly placed into one of two groups: One group will take tadalafil (5 mg), a medicine taken once a day. The other group will take solifenacin (5 mg), a common treatment for OAB, also taken once a day. The study will last 12 weeks. Participants will keep a bladder diary, answer short questionnaires, and have simple urine flow and bladder tests at several visits. The main goal is to find out which medicine lowers OAB symptoms more, such as urgency and frequent urination. Researchers will also look at quality of life, bladder function, and side effects. Women aged 18 to 75 years with OAB symptoms for at least 3 months may be able to take part.

This description comes directly from the study's public registry record.

Talk to the study team

Mohammed Hegazy, M.D of Urology  ·  +201028299216  ·  mhalem88@yahoo.com

Yahya H ElMorsy, MSc of Urology  ·  +201100311999  ·  hossam.yahya@yahoo.com

Always discuss trial participation with your own doctor first.

Locations (14)

Faculty of medicine, Menofia UniveristyShibīn al Kawm, Al-Minūfiyyah, EgyptRecruiting
Faculty of medicine, Zagazig UniversityZagazig, Al-Sharqia, EgyptRecruiting
Urology and Nephrology Center, Mansoura UniversityAl Mansurah, Dakahlia Governorate, EgyptRecruiting
Faculty of medicine, Tanta UniversityTanta, Gharbia Governorate, EgyptRecruiting
faulty of medicine, Tanta UniveristyTanta, Gharbia Governorate, EgyptRecruiting
Faculty of medicine, minia universityAl Minyā, EgyptRecruiting
Faculty of medicine, Alexandria UniversityAlexandria, EgyptRecruiting
Faculty of medicine, Aswan universityAswān, EgyptRecruiting
Faculty of Medicine - Assiut UniversityAsyut, EgyptRecruiting
Faculty of Medicine - Banī Suwayf UniversityBanī Suwayf, EgyptRecruiting
Faculty of medicine, Ain Shams UniversityCairo, EgyptRecruiting
Cairo University, faculty of medicineCairo, EgyptRecruiting

+ 2 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07416968